World Rabies Day—28th September

Rabies Awareness

First written about in Mesopotamia in 1930 B.C. rabies has been around for 4,000640px-Werwolf years. Whilst the first medical record of rabies in a human was registered in Boston in 1768 (Baer, 1991), there are many other forms of records. Early medieval records depict lycanthropy as does ancient Greek literature, one of the most famous of woodcutting depicts a ’werewolf’ looking for all the world like a man gone mad.

In fact rabies is caused by lyssaviruses ‘lyssa derived from the word ‘lud’ or ‘violent’, ‘rabies’ from the Latin meaning ‘madness’.

Scratches or bites from an infected being spread the disease, causing acute inflammation of the brain leading to:-

  • Violent movements
  • Uncontrolled excitement
  • Anxiety
  • Agitation
  • Paranoia
  • Hallucinations
  • Delirium
  • Fear of water, also unquenchable thirst
  • Inability to move parts of the body
  • Confusion
  • Loss of consciousness

Whilst the first stage of infection is characterised by behavioural changes, the second stage is known as “furious rabies”, where the infected have a tendency to be hyper-reactive to external stimuli and bite anything in their immediate vicinity, it is obviously at this stage when others are most likely to also become infected. The third and final stage is paralytic, signs being drooling, difficulty swallowing, facial paralysis, limb paralysis and eventually respiratory arrest. Once the infected have passed, they will look simply as they had prior to infection (remind you of any myths?).

The UK has been rabies free since 1922 after imposing compulsory quarantine for dogs entering the country and introduced ‘Pet Passports’ in 2001, a number of other countries are also rabies free.940px-Rabies_Free_Countries_Sourced_2010.svg

Whilst the pet passport system was first hailed as an invitation to bring Rabies into the country, it has so far proved efficacious. The system required however still entails a wait. In order to qualify your pet (dog, cat or ferret), must be microchiped or tattood prior to being given a rabies vaccination, and for dogs a tapeworm treatment. Thirty days after the rabies vaccine your pet is required to have a blood test proving that the vaccine was successful, a copy of which you are required to keep to present to passport control, not until three months after this test can your pet travel. Unfortunately the required blood test does not always pass, and repeat vaccinations are often required, along with further waits prior to travel.pet_passport

The first vaccine was developed by Louis Pasteur and Emile Roux in 1885 by taking nerve tissue from infected rabbits and allowing it to dry; another source of antibodies is consumption of infected birds after they have recovered (Gough & Jorgenson 1976, Jorgenson & Gough, 1976). Whilst rabies vaccine s are not currently 100% efficacious (Murray et al. 2009), and have a number of side effects:-

  • Immediate:
    • Vomiting
    • Facial Swelling
    • Fever
    • Lethargy
    • Circulatory Shock
    • Loss of consciousness
    • Death
  • Delayed onset
    • Cancer at site of injection
    • Seizures or epilepsy
    • Autoimmune disease
    • Allergies
    • Skin diseases
    • Muscle weakness
    • Chronic digestive disorders
    • Behaviour issues (Jan Rasmusen)

A new protocol of rabies vaccine manufacture has been identified as efficacious in all cases, this involves using membrane-anchored flagellin or Escherichia coli in the vaccine (Qi et al. 2015), long term testing is still required. However current vaccines are detailed by the manufacturer as providing immunity from 1-4 years, but legal requirements are either annual or tri-annual vaccination in the United States. Results of a seven year research project by Prof. Ronald Schultz is expected to show at least 7 years of immunity from one vaccine, indicating yet more mandated over-vaccination.

In exactly the same way as Cancer, Rabies requires an acidic environment and sugar (CDC , 2009) in order to replicate. If the history of lycantrophy is simply due to a lyssa virus contracted from a wild animal, or wolf with rabies, then it would make sense that these wolves were less afraid of people due to feeding on their refuse, taking in simple carbohydrates that are not species appropriate to their systems, hence leading them to have an acidic and sugar filled environment in which the rabies virus can successfully proliferate.

This being the case raw fed dogs on a species appropriate diet, containing no simple carbohydrates or sugars would be significantly less likely to contract this horrific, terminal disease.rabies

References:

Baer, G.M. (1991) The Natural History of Rabies. 2nd Ed. CRC Press Inc. United States

CDC (2009) Rabies Post-Exposure Prophylaxis [Internet] Available from: http://www.cdc.gov/rabies/exposure/postexposure.html (Accessed 30/1/2010)

Gough, P.M. Jorgenson, R.D. (1976) Rabies antibodies in sera of wild birds. Journal of Wildlife Diseases 12[3]:392-395

Jorgenson, R.D. & Gough, P.M. (1976) Experimental rabies in a great horned owl. Journal of Wildlife Diseases. 12[3]:444-447

Murray KO, Holmes KC, Hanlon CA. (2009) Rabies in vaccinated dogs and cats in the United States, 1997–2001. J Am Vet Med Assoc 235:691–5

Qi, Y. Kang, H. Zheng, X. Wang, H. Gao, Y. Yang, S. & Xia, X. (2015) Incorporation of membrane-anchored flagellin or Escherichia Coli heat-labile enterotoxin B subunit enhances the immunogenicity of rabies virus-like particles in mice and dogs. Frontiers in Microbiology. [Internet] Available from: http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00169/pdf (Accessed 18/02/2015)

 

Chemical Castration and Contraception

Non-surgical spay/neuter options

Several studies have established that surgical sterilisation raises significant health risks, particularly when performed at an early age; the most problematic of which is delayed closure of bony growth plates resulting in abnormal skeletal development that increases the incidence of orthopaedic problems such as hip dysplasia and patellar luxation.

Further studies have revealed that whilst spay surgery carries a high rate of complications, around 20%, such as infection, haemorrhage and even death, and that it the lack of oestrogen created leads to around 20-30% of spayed bitches developing urinary incontinence,  waiting to spay until after the age of six can increase longevity by 30%. Neutered males have an increased risk of prostate cancer (4 times the risk), both sexes have an increased risk of Osteosarcoma (bone cancer), haemagiosarcoma, hypothyroidism (triple the risk), obesity (3 times the risk), diabetes, urinary tract infections (3-4 times the risk), urinary tract cancer (double the risk), urinary incontinence and cognitive dysfunction in older pets. Behavioural studies have shown increased fearfulness, noise phobias and aggression.

If surgical sterilisation comes with all of the above risks, what about the new option of chemical castration?

According to vetinfo.com chemical castration with Neutersol, recently renamed Zeuterin and released onto the market in February of this year, is FDA approved as 99.6% effective, and can be used on males between 3 and 10 months old.  The chemical is injected into each testes and the amount provided is dependent on their diameter. Apparently it does not have a significant effect on testosterone production, and does not appear to effect behaviour and the animal may succumb to irritation and inflammation at the injection site. Zeuterin contains Zinc Gluconate and L-Arginine and works by destroying existing spermatozoa in both the seminiferous tubules and the epididymis, resulting in the collapse of the empty tubules, leaving scar tissue to block any further transport (Ark Sciences, 2014).

The side effects are listed as:

  • Scrotal pain one to three days after injectionPicture1
  • Mild, temporary swelling
  • Scrotal irritation or dermatitis
  • Low white blood cell count
  • Anorexia
  • Lethergy
  • Diarrhea

There are also contraceptives available to bitches, in drop or pill form. Mibolerone is a drop given daily for 30 days prior to the heat cycle, with side effects such as:

  • Liver damage
  • Infertility
  • Increased risk of vaginal infection and indoor wetting
  • Body odour
  • Skin problems
  • Vaginal distortion
  • Personality and behaviour changes

Ovaban is a pill to be administered at the beginning of the heat cycle, with side effects listed as:

  • Uterine infections
  • Mammarian cancer
  • Breast enlargement
  • Weight gain
  • Changes in coat

The question then becomes a philosophical one, which only the owner can answer, are you happy to take the risk, or simply separate your pets for 3 weeks once or twice a year?

We recommend reading: The Spay Neuter Health Denigration & checking out Voss Pets

Ark Sciences (2014) Zeuterin. [Online] Available from: http://www.arksciences.com/product.html (accessed 31/07/2014)

Image rights — All Critters Pet Hospital (2014) Zeuter vs Neuter tOnline] Available from: http://wallcritterpethospital.com/blog/b_38970_zeuter_vs_neuter_sterlize_your_male_dogs_without_putting_him_through_Surgery.html (accessed 31/07/2014)

 

Spotlight on…. Canine Transmissible Cancer

Infectious Canine Cancer

The percentage of canine cancer patients has grown exponentially in the last few decades, so much so that an Animal Cancer Registry was established in 1985. Research has established that 45% of dogs over the age of 10 are dying of cancer and an estimated 1 in 3 have the potential to develop it, with a prevalence in certain breeds, the highest risk being in:

  • Boxer
  • Golden Retriever (60% of breed mortality)
  • Rottweiller
  • Bernese Mountain Dog

The risks are higher in female than male dogs due to mammary cancer accounting for 70% of all incidences (Merlo et al. 2008), and three to four times higher in spayed and neutered pets (Torres et la Riva et al. 2013).

Whilst many holistic owners believe that this is due to the combination of commercial food products, vaccines and other chemicals that our pets are exposed to, there has been recent media coverage of a transmissible cancer, which is scarier still.

Picture1Canine Transmissible Venereal Tumour (CTVT) is a unicellular pathogen, where the infectious agent is the cancerous cell itself. Microsatellite analysis indicates this tumour is over 6,000 years old and originated back when dogs were first domesticated.

 

The vector is sexual, cells reproduce on the new host over a period of two to six months to form a tumour-like growth usually around the genitalia.

Picture2    Picture3

Without treatment these tumours usually regress due to the hosts natural immune response (Siddle & Kaufman, 2014) after one to three months and with complete regression comes complete immunity (Rebbeck et al. 2009).

CTVT is one of only two known communicable cancers and the oldest cancer in the natural world (Lakody, 2014). DNA analysis shows that CTVT first occurred in a dog with “low genetic hetrozygosity” (i.e. that was highly inbred) 11,000 years ago, therefore it was initiated due to human selective breeding (Murchison et al. 2014).

CTVT is prevalent in at least 90 countries and all inhabited continents, and is estimated to have infected at least one percent or more of dogs in at least 13 countries in South and Central America, as well as at least 11 countries in Africa and 8 in Asia.

Picture4

In the USA and Australia it has only been reported in remote indigenous communities and prevalence has declined in Northern Europe. This disease is mostly prevalent in areas with free roaming canines and has disappeared from the UK (Strakova, 2014).

Surgical removal of tumours has been shown to leave a 30% reoccurrence rate, however this was only studied in 10 dogs, the same study found no recurrence in 10 dogs given chemotherapy, but these dogs were only followed for six months (Awan et al. 2014). CTVT tumours are generally not fatal as the hosts’ immune response controls or clears the tumours after transmission and a period of growth (Siddle & Kaufman, 2014), however metastasis does occur in immune-suppressed animals. The most immediately effective allopathic therapy has been reported to be ‘Vincristine’ (VCR) also used as an immunosuppressant, with known side effects of:

  • Vomiting
  • Diarrhea
  • Low White Blood Cell Count
  • Bladder Irritation (Canine Cancer Library, 2014)
  • Chemical burns on skin contact

 

Picture5Therefore if a strong immune system, developed from a natural balanced diet, preferably through generations of dogs, as Epigenetics have been shown to be a contraction factor (Siddle & Kaufman, 2013) can destroy these tumours and render the host non-susceptible to reinfection, is the recommended protocol of surgery and chemotherapy (Awan et al. 2014) simply not worth the risk of metastasis, (as one single cell left on an immune compromised animal could lead to this) and further damage that these leave particularly for natural rearers, and future genetics, dependent of course on the severity of the tumour?

N.B. For further details on the risks of spaying and neutering please see Turner, H. (2014) “The Spay/Neuter Health DenigrationHealthful Dog 1[2]:52-53

References:

Awan, F. Ali, M.M. Ijaz, M. & Khan, S. (2014) Comparison of Different Therapeutic Protocols in the Management of Canine Transmissible Venereal Tumour: Review of 30 Cases. Global Veterinaria. 12[4]:499-503

Canine Cancer Library (2014) Common Chemotherapy Side Effects. Available from: http://www.wearethecure.org/chemotherapy-side-effects (Accessed 16/11/2014)

Lokody, I. (2014) The Origin and Evolution of an Ancient Cancer. Cancer Genetics. 14:152

Merlo, D.F. Rossi, L. Pelligrino, C. Ceppi, M. Cardellino, U. Capurro, C. Ratto, A. Sambucco, P.L. Sestito, V. Tanara, G. & Bocchini, V. (2008) Cancer incidence in pet dogs: findings of the Animal Tumor Registry of Genoa, Italy. Journal of Veterinary Internal Medicine. 22[4]:976-984

Murchison. E.P. Wedge, D.C. Alexandrov, L.B. Fu, B. Martincorena, I. Ning, Z. Tubio, J.M.C. Werner, E.I. Allen, J. De Nardi, A.B. Donelan, E.M. Marino, G. Fassati, A. Campbell, P.J. Yang, F. Burt, A. Weiss, R.A. & Stratton, M.R.  (2014) Transmissible Dog Cancer Genome reveals the Origin and History of an Ancient Cell Lineage. Science. 343:437-440

Rebbeck, C.A. Thomas, R. Breen, M. Leroi, A.M. & Burt, A. (2009) Origins and Evolution of a Transmissible Cancer. Evolution. 63[9]:2340-2349

Siddle, H.V. & Kaufman, J. (2013) A tale of two tumours: Comparison of the immune escape strategies of contagious cancers. Molecular Immunology 55[2]:190-193

Siddle, H.V. & Kaufman, J. (2014) Immunology of Naturally Transmissible Tumours. Immunology. DOI: 10.1111/imm.12377

Strakova, A. & Murchison, E.P. (2014) The Changing Global Distribution and Prevalence of Canine Transmissible Venereal Tumour. BMC Veterinary Research. 10:168

Torres de la Riva, G. Hart, B.L. Farver, T.B. Oberbauer, A.M. Locksley, L. McV. Messam, N.W.  & Hart, L.A. (2013) Neutering Dogs: Effects on Joint Disorders and Cancers in Golden Retrievers. PLOS DOI: 10.1371/journal.pone.0055937

 

The Phenol Allergen Issue

How do food allergies effect pets?

An allergy is an inappropriate and excessive reaction of the immune system to an allergen.

Allergies manifest as:

  • Itching
  • Infections of the skin and ear
  • Hot Spots
  • Chronic diarrhoea and/or IBD
  • Vomiting
  • Seizures
  • Behaviour Problems/Hyperactivity
  • Pancreatitis
  • Chronic Liver Disease
  • Lethargy
  • Cancer

Food Allergies

The most common food allergens for dogs are Chicken and Beef, we understand that these are mainly due to vaccines reactions, in that vaccine components are often grown in chicken embryo/bovine serum etc. therefore Chicken and Beef are the first proteins recommended to be removed from an animals diet when an allergy is suspected.

The next most common allergen, known to cause all sorts of bowel issues due to food sensitivities and intolerances are caused by Phenols i.e. Gallic Acid

Gallic Acid is found in many fruit and vegetables, including, but not restricted to:

Whilst Food Allergies cause immediate reactions, food sensitivities and intolerances have a delayed response. They may start as simple itching and progress down the above reactions list to cancer if fed even in small amounts on a regular basis.

Let us not forget that the microbiome in the bowel represents 80% of the immune system and if that is negatively effected, exposure to something else that would normally cause a mild reaction, could actually end up being catastrophic.

Due to this and other issues with these foods we do not recommend feeding them, especially on a regular basis.

Spotlight on Ethyl vs Methyl Mercury

Ethyl vs Methyl Mercury

Ethyl mercury is the type found in vaccines, the CDC website says that it differs from Methyl mercury (found in fish, amalgam fillings and the environment) in that it leaves the blood stream much more quickly and is therefore less toxic.

Studies have shown that Ethyl mercury leaves the blood stream within 7 days, where as Methyl mercury takes 54 days to leaving the blood stream, which supports this statement. However, Ethyl mercury was not found to be excreted from the body, in fact, whilst it does leave the blood stream, it crosses the blood brain barrier and goes directly to the brain, where it stays (Burbacher).

Unfortunately Ethyl mercury is metabolised into inorganic mercury at twice the rate that Methyl mercury does, which causes neurological damaged and neurological death in the brain and is 50 times more toxic than Methyl mercury to the brain (Guzzi et al. 2012).

Thimerosal was released in 1931, the same year as the first ever diagnosis of Autism. It was found to be toxic in parts per billion, which had never been witnessed before and when tested on dogs, all test animals died; as for human testing, 22 test subjects who were suffering from meningitis were given Thimerosal, or Merthiolate (CgHgHgNaO2S) as it was then known, all test subjects died, most within 24 hours, however it was considered that they died of the meningitis and it is therefore safe.

The symptoms of Mercury Poisoning and Autism equate line for line.

One study showed that when comparing the risk of autism diagnosis  in those who had received under 25µg of thimerosal to those who had received over 25µg, the risks of autism were between 762 and 1135 times higher in those with greater exposure, they also discovered that the risks of ADD, ADHD, ticks, speech delay, sleep disorders and a number of other neuro-developmental disorders had similar statistics (Verstraeten, 1999). As thimerosal does not appear to dissipate from the brain, you can now begin to understand why over-vaccinating causes so many issues.

There are in fact hundreds of studies linking thimerosal to autism, and billions of dollars that have been awarded to children who’s parents have proven that their child was damaged by vaccines.

However, there are very few people who are trying to raise awareness of the damage caused by vaccines in pets. We are very proud that Catherine O’Driscoll of Canine Health Concern, who works tirelessly to raise awareness and work on improving safety, writes for us and that we are able to share information from the likes of Patricia Jordan, Jean Dodds and Ronald Schultz.

We have written previously on the fact that pets get autism (Healthful Dog 1[2] December 2014), and will continue to work to raise awareness. Meanwhile, we eagerly look forward to the release of Catherine O’Driscoll’s next book.

The maximum recommendation of oral mercury ingestion is based on Methyl Mercury and set at 1.6 µg per kilogram of bodyweight, this is set from human consumption, but as tests in the ‘30s showed, this may not be relevant for dogs.

  • Dog and Cat vaccines are generally 1ml
  • According to the FDA pet vaccines contain 1 microgram (µg) of Thimerosal or less.

Thimerosal is 50% Ethyl Mercury, therefore based on these statistics a pet weighing 0.3kg or more, should have no issue with 1 vaccine. However, as we know, more than one is generally given at a time.

Maths

  • 0.5µg of Ethyl Mercury per vaccine
  • Ethyl Mercury converts to Inorganic Mercury at twice the rate of Methyl Mercury

= 1µg per vaccine.

  • It’s 50 times more toxic

= 50µg per vaccine

  • And when combined with aluminium (connected to auto-immunity & Alzheimer’s) is 6 times more corrosive

= 300µg per vaccine

  • When combined with Testosterone the risks are 4 fold (Boyde, 2005)

 

So for a healthy pet, to be able to cope with the Mercury levels in 1ml of  one vaccine, according to science based on a different form of mercury, based on human studies, of oral, not intramuscular or intravenous administration, it would have to weigh:

 

Female: 187.5kg                                 Male: 750 Kg

 

How much does your dog or cat weigh?

 

The body can excrete Mercury with the aid of the antioxidant Glutathione (Pompella et al. 2003), the issue with those susceptible to Autism is that their glutathione production is very low, and is lowered still by the presence of mercury. Due to the mode of action of glutathione, a glutathione supplement does not work, you need to increase the body’s natural production.

The best way we know of doing this is by taking/giving the supplement ASEA, which increases glutathione production by between 500 and 800% with radox signalling molecules.

ASEA is available via our website.

http://www.healthfuldog.co.uk

Sources:

RFK Jr. 2017 Vaccines Revealed Episode 3 [Internet] VaccinesRevealed.com

Trace Amounts (movie)

Turner, H.B. (2017) Spotlight on Ethyl vs Methyl Mercury. Healthful Dog 4[1]:56-57

Welcome

H B Turner (Hope) has spent decades learning about natural health for people & pets, and shares what she’s learnt.

Hope had taken numerous courses, learnt from incredible mentors and has tailored her Foundation Degree [FdSc] and Bachelors [BSc (Hons)] to nutrition and holistic health.

Having started a Masters in Clinical Nutrition and consulted on health for over 15 years she can offer a range of natural solutions to your issues.

Her mission is to increase health via nutrition, supplementation and toxin elimination by giving you the tools to create a healthier lifestyle.

Consultations currently available at:

Hear4U offices – Leicester

Facebook | Instagram | Twitter | YouTube